Wisconsin MPJE (Pharmacy Jurisprudence) Practice Exam

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What are the requirements for diphenoxylate/atropine to be classified under Schedule V?

Not more than 1 mg of diphenoxylate with not less than 25 mcg of atropine per dosage unit
Not more than 1 mg of diphenoxylate with not less than 2.5 mcg of atropine per dosage unit
Not more than 2.5 mg of diphenoxylate with not less than 25 mcg of atropine per dosage unit
Not more than 2.5 mg of diphenoxylate with not less than 50 mcg of atropine per dosage unit

The correct answer is: Not more than 1 mg of diphenoxylate with not less than 25 mcg of atropine per dosage unit

The correct answer is A. Schedule V drugs have the lowest potential for abuse and are considered to have accepted medical uses. Therefore, the ratio of active ingredients in diphenoxylate/atropine must be carefully balanced to minimize risk of abuse. Option B has a smaller amount of atropine, which may not be as effective in preventing abuse. Option C has a larger amount of diphenoxylate, which may increase the risk of abuse and potential harm to patients. Option D has a larger amount of atropine, which may increase the risk of side effects and limit the availability of the medication for medical purposes.